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[Titration plates – fast heat transfer thanks to thin-wall technology]

Titration plates
OEM: Various
Supplier: Nelipak, Venray (NL)
Industry sector: Titration plates


Part design:

Titration plates with 96 cavities are widely used in medical and biotech laboratories. Small amounts of substances are located in the tiny V-shaped cavities and sent for analysis. Initially, Nelipak made these titration plates from PVC and PETG. A change to the testing program involving rapid temperature fluctuations between 50 °C and 105 °C meant that an alternative material was required. Makrofol® DE 1-4 extruded film proved ideal because it is heat resistant to 135 °C and also benefits from lower internal stresses than competitors’ materials. This makes it possible to mold the 96 cavities without cracks developing, using a fully automatic high-precision thermoforming process with minimal stresses and distortion. The temperatures of the mold coated on one side are controlled to within ± 3 °C in order to comply precisely with the cavity wall thinness required for certain analyses to enable rapid heat transfer through the film from heating blocks onto the substances to be tested. The plates are produced in a Class 10000 cleanroom and individually packaged.

Another reason for choosing Makrofol® DE 1-4 was the fact that it does not release any chemicals and only small amounts of protein adhere to its surface.

heat resistance to 135 °C
rapid heat transfer through the thin film
minimal adhesion of protein to the surface
no release of inhibitory chemicals
low-stress and low-warp


Detailed Information:
Product: